Expresión de búsqueda: EUKARYOTIC INITIATION FACTOR-3 
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Descriptor Inglés:   Eukaryotic Initiation Factor-3 
Descriptor Español:   Factor 3 de Iniciación Eucariótica 
Descriptor Portugués:   Fator de Iniciação 3 em Eucariotos 
Sinónimos Inglés:   EIF-3
Peptide Initiation Factor EIF-3  
Categoría:   D12.776.835.725.868.437
Definición Inglés:   A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit. 
Nota Histórica Inglés:   2003; use EUKARYOTIC INITIATION FACTOR-3 (NM) 1990-2002 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   37526 
Identificador Único:   D039621 

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